Nature Medicine - About the cover: Using CRISPR-Cas9–based genome editing technology, Sato and colleagues (featured on p 256 of this month's issue) introduce various combinations of mutations associated with human intestinal tumors
![Single-dose CRISPR-Cas9 therapy extends lifespan of mice with Hutchinson-Gilford progeria syndrome. - Nat. Med. - X-MOL Single-dose CRISPR-Cas9 therapy extends lifespan of mice with Hutchinson-Gilford progeria syndrome. - Nat. Med. - X-MOL](https://xpic.x-mol.com/20190220%2F10.1038_s41591-019-0343-4.jpg)
Single-dose CRISPR-Cas9 therapy extends lifespan of mice with Hutchinson-Gilford progeria syndrome. - Nat. Med. - X-MOL
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Nature Medicine on Twitter: "#CRISPR–Cas9-induced DNA damage triggers p53 to limit the efficiency of #geneediting in immortalized human retinal pigment epithelial cells: https://t.co/Ofc8akirQF… https://t.co/jA1qViiOE7"
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Nature Medicine on Twitter: "Two studies find that #AAV-mediated #CRISPR/ Cas9 therapy extends life span and ameliorates disease-related phenotypes in a mouse model of #progeria. https://t.co/2LfOogSXLX and https://t.co/y5KjuD5Yjb… https://t.co/RMaa25wQoI"
![The next generation of CRISPR–Cas technologies and applications | Nature Reviews Molecular Cell Biology The next generation of CRISPR–Cas technologies and applications | Nature Reviews Molecular Cell Biology](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41580-019-0131-5/MediaObjects/41580_2019_131_Fig1_HTML.png)
The next generation of CRISPR–Cas technologies and applications | Nature Reviews Molecular Cell Biology
CRISPR-cas gene-editing as plausible treatment of neuromuscular and nucleotide-repeat-expansion diseases: A systematic review
![Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects | Signal Transduction and Targeted Therapy Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects | Signal Transduction and Targeted Therapy](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41392-019-0089-y/MediaObjects/41392_2019_89_Fig1_HTML.png)